Our application window is now live!
We are looking for fresh thinking and the brightest minds to join us in bringing AI to the fight against ALS.
Entries are open from Wednesday 25th June 2025 - Wednesday 3rd December 2025.
Longitude Prize on ALS
The £7.5 million (~$10 million) Longitude Prize on ALS incentivises the use of AI-based approaches to transform drug discovery for amyotrophic lateral sclerosis (ALS), the most common form of motor neurone disease (MND).
Overview of the Prize
Interested in learning more about the Prize? Watch this to get an overview of how it works.
Timeline of the Prize
The Longitude Prize on ALS will run for five years and will comprise three key stages: Discovery, Prioritise and Validate
Interested in the Prize?
Whether you want to enter, provide support to teams, or just keep up with our progress, register below as a team or join our mailing list.
Latest events
Webinars
Welcome webinar #1
9 July 25
This was a live session to learn more about the Prize. Members of the Prize management team introduced the Longitude Prize on ALS, its aims, how the application process works, and what you need to know to take part.
Sign up now
Webinars
Welcome webinar #2
10 July 25
This was a live session to learn more about the Prize. Members of the Prize management team introduced the Longitude Prize on ALS, its aims, how the application process works, and what you need to know to take part.
Sign up now
Webinars
Data showcase webinar
28 August 25
Join leading voices in ALS and key data partners as we showcase the datasets and tools available to Prize entrants. Discover how our comprehensive data will support AI-driven approaches in identifying new treatment targets.
Sign up now